Waterkloof is a highly sought-after area and has some of the city's most expensive real estate, including hilltop homesteads on Edward and Victoria Streets with views of Pretoria. Like many areas of the city, its streets are lined with jacaranda trees. Many streets are named after British royalty; the main thoroughfares are Crown Avenue, which links Waterkloof with the affluent suburb of Brooklyn to its north, and Albert Street, which runs East-West between the neighbouring areas of Menlo Park and Groenkloof.
Several ambassadorial residences are located in Waterkloof. It is the home of soprano Mimi Coertse, and the location of the upmarket Dube-house in the film Tsotsi. Pretoria Country Club, which has an eighteen-hole golf course, is also located in the area.